Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28449062 | 0.95 | KDM4E (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| Sulfuric Acid SCHEMBL4245147 | 0.95 | KDM4E (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| Sulfuric Acid SCHEMBL28980889 | 0.95 | KDM4E (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL2293455 | 0.94 | ABCB11 (0.41) | — | |
| Sulfuric Acid SCHEMBL316621 | 0.93 | KDM4E (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL193628 | 0.93 | KDM4E (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL7742084 | 0.92 | KDM4E (0.37) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| Sulfuric Acid SCHEMBL582397 | 0.92 | SMN1; SMN2 (0.36) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL28673400 | 0.92 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTSMN1; SMN2HTT | |
| Sulfuric Acid SCHEMBL29028943 | 0.90 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108885367-B | Polarizing plate and liquid crystal display including the same | 株式会社LG化学 | 2021-09-07 | — | — | CN | disclosed |