SCHEMBL2865295

SCHEMBL2865295

CC(=CC(C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13685332 0.77 APEX1 (0.35) APEX1
SCHEMBL536916 0.77 APEX1 (0.35) APEX1
SCHEMBL28609318 0.76
SCHEMBL13685385 0.76 TSHR (0.33) APEX1
SCHEMBL642406 0.76 TSHR (0.33) APEX1
SCHEMBL8150337 0.76 TSHR (0.44) APEX1
SCHEMBL3311523 0.76 APEX1 (0.31) APEX1
SCHEMBL28712283 0.75 KDM4E (0.35)
SCHEMBL28033659 0.74 PTGS1 (0.33) APEX1
SCHEMBL20566959 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191072-B1 Electropolymerization modified carbon black and articles including tires having at least one component containing such modified carbon black GOODYEAR TIRE & RUBBER (US) 2006-01-04 EP claimed
US-6894103-B2 Surface treated carbon black; tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-05-17 US claimed
US-20030073775-A1 Surface treated carbon black; tires THE GOODYEAR TIRE & RUBBER COMPANY. 2003-04-17 US claimed
US-6512040-B1 Method of preparing an electropolymerization modified carbon black which comprises the steps of treating carbon black particles and/or carbon black fibers by: forming a functional polymer by electropolymerization onto the surface of carbon THE GOODYEAR TIRE & RUBBER COMPANY 2003-01-28 US claimed
EP-1191072-A2 Electropolymerization modified carbon black and articles including tires having at least one component containing such modified carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-03-27 EP claimed
US-7816460-B2 Low polydispersity poly-HEMA compositions JOHNSON & JOHNSON VISION CARE, INC. (US) 2010-10-19 US disclosed
EP-1567567-B1 LOW POLYDISPERSITY POLY-HEMA COMPOSITIONS JOHNSON & JOHNSON VISION CARE (US) 2010-09-08 EP disclosed
US-7585074-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2009-09-08 US disclosed
US-7401922-B2 Method and apparatus for reducing or eliminating the progression of myopia SYNERGEYES, INC. (US) 2008-07-22 US disclosed
US-7322694-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2008-01-29 US disclosed
US-20080015322-A1 LOW POLYDISPERSITY POLY-HEMA COMPOSITIONS JOHNSON & JOHNSON VISION CARE, INC. 2008-01-17 US disclosed
US-7256246-B2 Low polydispersity poly-hema compositions JOHNSON & JOHNSON VISION CARE, INC (US) 2007-08-14 US disclosed
US-5786435-A COATINGS; WATER RESISTANCE, CHEMICAL RESISTANCE, WEAR RESISTANCE MAZDA MOTOR CORPORATION (JP) 1998-07-28 US disclosed
EP-0530360-A4 PHILLIPS PETROLEUM CO (US) 1995-04-26 EP disclosed
US-5371147-A Silicone-containing acrylic star polymers, block copolymers and macromonomers PERMEABLE TECHNOLOGIES, INC. (US) 1994-12-06 US disclosed
US-5314961-A Acrylic-silicone polymers PERMEABLE TECHNOLOGIES, INC. (US) 1994-05-24 US disclosed
US-5314960-A Silicone-containing polymers, oxygen permeable hydrophilic contact lenses and methods for making these lenses and treating patients with visual impairment PERMEABLE TECHNOLOGIES, INC. (US) 1994-05-24 US disclosed
EP-0552306-A1 NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM PERMEABLE TECHNOLOGIES, INC. (US) 1993-07-28 EP disclosed
EP-0530360-A1 GLASS-REINFORCED GRAFTED BRANCHED HIGHER ALPHA-OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1993-03-10 EP disclosed
WO-1992007013-A1 NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE HYDROPHILIC CONTACT LENSES THEREFROM PERMEABLE TECHNOLOGIES, INC. (US) 1992-04-30 WO disclosed