Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642406 | 1.00 | TSHR (0.33) | TSHRHCAR2APEX1GRIK1GRIA2 | |
| SCHEMBL28033659 | 0.84 | PTGS1 (0.33) | APEX1PTGS1 | |
| SCHEMBL475010 | 0.83 | APEX1 (0.33) | APEX1 | |
| SCHEMBL536916 | 0.79 | APEX1 (0.35) | APEX1PTGS1AKR1C3 | |
| SCHEMBL13685332 | 0.79 | APEX1 (0.35) | APEX1PTGS1AKR1C3 | |
| SCHEMBL3311523 | 0.77 | APEX1 (0.31) | APEX1PTGS1AKR1C3 | |
| SCHEMBL8150337 | 0.77 | TSHR (0.44) | TSHRHCAR2APEX1PTGS1AKR1C3 | |
| SCHEMBL16649061 | 0.77 | LMNA (0.38) | — | |
| SCHEMBL2865295 | 0.76 | APEX1 (0.30) | APEX1 | |
| SCHEMBL8726425 | 0.75 | PTGS1 (0.37) | APEX1GRIK1GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776399-B1 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS | UNIV GENT (BE) | 2012-11-14 | — | — | EP | claimed |