Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | CD38 | P28907 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658005 | 0.86 | RAB9A (0.59) | RAB9ANPC1PARP1CD38KDM4E | |
| SCHEMBL28647447 | 0.85 | ADRA1D (0.53) | RPS6KB1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL30311518 | 0.82 | HSD17B10 (0.63) | RPS6KB1PARP1CD38KDM4EPOLB | |
| SCHEMBL2754257 | 0.82 | HSD17B10 (0.63) | RPS6KB1PARP1CD38KDM4EPOLB | |
| SCHEMBL28658000 | 0.81 | AURKA (0.65) | RPS6KB1RAB9ANPC1PARP1CD38 | |
| SCHEMBL28181760 | 0.78 | SIRT2 (0.60) | SIRT2SIRT1 | |
| SCHEMBL20680388 | 0.76 | CD38 (0.80) | CD38 | |
| SCHEMBL30802642 | 0.76 | PARP1 (0.75) | RPS6KB1RAB9ANPC1PARP1KDM4E | |
| SCHEMBL29200370 | 0.76 | PARP1 (0.75) | RPS6KB1RAB9ANPC1PARP1KDM4E | |
| SCHEMBL3441356 | 0.76 | AGTR1 (0.54) | RAB9ANPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563272-B | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113563272-A | Preparation method of 2-phenylquinazolinone compound | 三峡大学 | 2021-10-29 | — | — | CN | disclosed |