Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30823799 | 0.83 | DDB1 (0.56) | DDB1CRBNKMT2AMEN1LMNA | |
| SCHEMBL28644757 | 0.83 | DDB1 (0.56) | DDB1CRBNKMT2AMEN1LMNA | |
| SCHEMBL28645239 | 0.81 | TDP1 (0.44) | DDB1CRBNMMP1MMP13LMNA | |
| SCHEMBL28926766 | 0.81 | DDB1 (0.45) | DDB1CRBNKMT2ALMNATSHR | |
| SCHEMBL28653243 | 0.77 | MMP13 (0.43) | DDB1CRBNMMP13KMT2AMEN1 | |
| SCHEMBL3172306 | 0.77 | DDB1 (0.50) | DDB1CRBNMMP1MMP13LMNA | |
| SCHEMBL30823806 | 0.75 | DDB1 (0.51) | DDB1CRBNMMP1MMP13LMNA | |
| SCHEMBL27965543 | 0.71 | CRBN (0.71) | DDB1CRBNMMP1MMP13LMNA | |
| SCHEMBL28648510 | 0.71 | DDB1 (0.47) | DDB1CRBNMMP1MMP13LMNA | |
| SCHEMBL28652610 | 0.71 | DDB1 (0.47) | DDB1CRBNMMP1MMP13KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |