Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 10/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869305 | 0.73 | SMPD1 (0.36) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL7691167 | 0.71 | TSHR (0.38) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL8926905 | 0.71 | TSHR (0.38) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL8532581 | 0.71 | TSHR (0.38) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL7755461 | 0.65 | FDPS (0.37) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL3482197 | 0.65 | FDPS (0.33) | TSHRFDPS | |
| SCHEMBL3482619 | 0.65 | FDPS (0.33) | TSHRFDPS | |
| SCHEMBL4200268 | 0.62 | TSHR (0.44) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL7623988 | 0.62 | FDPS (0.48) | SMPD1TSHRTHRBFDPSGGPS1 | |
| SCHEMBL10882953 | 0.62 | TSHR (0.38) | TSHRTHRBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901690-A | Treatment of cancer with Antibody Drug Conjugates (ADCs) that bind 191P4D12 protein | 艾更斯司股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-113677364-A | Pharmaceutical compositions comprising anti-191P 4D12 antibody drug conjugates and methods of use thereof | 艾更斯司股份有限公司 | 2021-11-19 | — | — | CN | disclosed |