SCHEMBL869305

SCHEMBL869305

CCCCCC(C)(C)[SiH2]O[SiH2]C(C)(C)CCCCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.36
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
FDPS P14324 11/20 0.32
GGPS1 O95749 7/20 0.32
CES2 O00748 1/20 0.30
LPAR1 Q92633 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7773376 0.81 SMPD1 (0.38) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL6883229 0.81 SMPD1 (0.38) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL6892063 0.81 SMPD1 (0.38) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL5376060 0.81 SMPD1 (0.38) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL2058036 0.74 SMPD1 (0.38) SMPD1TSHRFDPSGGPS1
SCHEMBL8472572 0.74 TSHR (0.44) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL28654057 0.73 SMPD1 (0.35) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL2058259 0.73 SMPD1 (0.37) SMPD1TSHRFDPSGGPS1
SCHEMBL1030960 0.72 FDPS (0.37) SMPD1TSHRTHRBFDPSGGPS1
SCHEMBL8756198 0.72 SMPD1 (0.42) SMPD1FDPSGGPS1CES2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024489-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2024-01-25 US claimed
EP-4247828-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF Institut Pasteur (FR) 2023-09-27 EP claimed
CN-116601163-A Protected disaccharides, methods for their preparation, their use in the synthesis of zwitterionic oligosaccharides and conjugates thereof 巴斯德研究所 2023-08-15 CN claimed
WO-2022106703-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF INSTITUT PASTEUR (FR) 2022-05-27 WO claimed
EP-2049689-B1 NUCLEIC ACID AMPLIFICATION USING A REVERSIBLY MODIFIED OLIGONUCLEOTIDE BI WANLI (US) 2011-12-21 EP claimed
EP-3494996-B1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS AGENSYS INC (US) 2026-04-15 EP disclosed
US-20260034234-A1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS AGENSYS, INC. (US) 2026-02-05 US disclosed
US-20260000604-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-191P4D12 ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF AGENSYS, INC. (US) 2026-01-01 US disclosed
US-12496353-B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway SEAGEN INC. (US) 2025-12-16 US disclosed
EP-4604951-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF AMIRA THERAPEUTICS, S.L. (ES) 2025-08-27 EP disclosed
CN-111330016-B Antibody Drug Conjugates (ADCs) that bind 158P1D7 protein 艾更斯司股份有限公司 2025-03-25 CN disclosed
US-12257340-B2 Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof AGENSYS, INC. (US) 2025-03-25 US disclosed
EP-1412346-B1 METHOD FOR PRODUCING NOVEL SPINOSYN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2005-03-09 EP disclosed
US-6280897-B1 GENERATION OF ACID WITH ACTINIC RADIATION KABUSHIKI KAISHA TOSHIBA (JP) 2001-08-28 US disclosed
US-6271370-B1 REACTING 2',3'-O-ALKYLIDENE .BETA.-FURANOSYL HALIDE COMPOUND WITH HETEROCYCLE HAVING RING NITROGEN CAPABLE OF FORMING COVALENT BOND WITH ANOMERIC CARBON OF FURANOSE OR FURANOSE ANALOG IN DIMETHYL SULFOXIDE IN PRESENCE OF STRONG BASE PFIZER INC 2001-08-07 US disclosed
EP-1052264-A2 Process for the synthesis of nucleoside analogs Pfizer Products Inc. (US) 2000-11-15 EP disclosed
US-6071670-A PHOTORESIST RESIN COMPRISING PHOTOACID GENERATING COMPOUND AND AN ACID HYDROLYZABLE OLIGOMER HAVING ALICYCLIC OR POLYCONDENSED AROMATIC BACKBONE; ALKALI DEVELOPMENT WITH HIGH RESOLUTION, DRY ETCH RESISTANCE KABUSHIKI KAISHA TOSHIBA (JP) 2000-06-06 US disclosed
US-5932391-A CONTAINING AN ACYCLIC COMPOUND WHICH IS A VINYL POLYMERBEING LIGHT ABSORBENT KABUSHIKI KAISHA TOSHIBA (JP) 1999-08-03 US disclosed
US-5863699-A FORMS A PATTERN THROUGH LIGHT-EXPOSURE WITH EITHER ARGON FLUORIDE OR FLUORINE EXCIMER LASERS, COMPRISES A COMPOUND HAVING EITHER AN ACID-DECOMPOSABLE OR ACID-CROSSLINKABLE GROUP KABUSHIKI KAISHA TOSHIBA (JP) 1999-01-26 US disclosed
EP-0463470-A2 Process for the preparation of a fluorotetrahydrofuranone derivative F. HOFFMANN-LA ROCHE AG (CH) 1992-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12496353-B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway MTOR, RICTOR, PIK3R5 SMPD1 1760/4885TSHR 2706/4885THRB 2976/4885
US-20240024489-A1 PROTECTED DISACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE IN THE SYNTHESIS OF ZWITTERIONIC OLIGOSACCHARIDES, AND CONJUGATES THEREOF SI, DAD1, FUT5 SMPD1 137/4885TSHR 3240/4885THRB 4149/4885
US-20260000604-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-191P4D12 ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF CD44, CA12, H1-10 SMPD1 366/4885TSHR 2385/4885THRB 1052/4885
US-12257340-B2 Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof TMED10, CD44, CA12 SMPD1 547/4885TSHR 3281/4885THRB 3416/4885
US-20260034234-A1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS IGSF11, ARID2, DYNLL2 SMPD1 1586/4885TSHR 3069/4885THRB 2812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.