Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23500743 | 0.78 | DRD2 (0.40) | PNMTDRD2NAMPT | |
| SCHEMBL28972016 | 0.78 | PSEN1 (0.40) | — | |
| SCHEMBL27689519 | 0.76 | PNMT (0.40) | PNMT | |
| SCHEMBL28445305 | 0.76 | PNMT (0.36) | PNMT | |
| SCHEMBL30685660 | 0.75 | IDO1 (0.54) | — | |
| SCHEMBL29593839 | 0.73 | PNMT (0.49) | PNMTDRD2DRD3KDM1A | |
| SCHEMBL4735015 | 0.73 | PNMT (0.49) | PNMTDRD2DRD3KDM1A | |
| SCHEMBL28448081 | 0.73 | PNMT (0.43) | PNMT | |
| SCHEMBL29187437 | 0.72 | LRRK2 (0.45) | PNMTDRD2DRD3KDM1A | |
| SCHEMBL29187438 | 0.72 | LRRK2 (0.45) | PNMTDRD2DRD3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710663-A | Modulators of MYC family proto-oncogene proteins | 纳罗医疗公司 | 2021-11-26 | — | — | CN | disclosed |