Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 13/20 | 0.54 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.44 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293667 | 0.92 | PLK1 (0.52) | PLK1KDM6BKDM4CPLK3CISD1 | |
| SCHEMBL9824061 | 0.90 | PLK1 (0.64) | PLK1KDM6BKDM4CPLK3CISD1 | |
| SCHEMBL28110422 | 0.86 | PLK1 (0.67) | PLK1KDM6BKDM4CPLK3CISD1 | |
| SCHEMBL28295487 | 0.86 | PLK1 (0.47) | PLK1KDM6BKDM4C | |
| SCHEMBL28109945 | 0.80 | PLK1 (0.67) | PLK1PLK3CISD1TRPM2HCAR3 | |
| SCHEMBL28655003 | 0.78 | KDM4E (0.53) | KDM6BKDM4CCISD1 | |
| SCHEMBL28295475 | 0.77 | HPGD (0.55) | PLK1KDM6BKDM4C | |
| SCHEMBL22097708 | 0.76 | HCAR3 (0.60) | PLK1KDM6BKDM4CCISD1HCAR3 | |
| SCHEMBL29033346 | 0.75 | KDM6B (0.57) | PLK1KDM6BKDM4CCISD1HCAR3 | |
| SCHEMBL5386530 | 0.75 | PLK1 (0.58) | PLK1KDM4CPLK3TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651179-B | 2- (2-aminobenzoyl) benzoic acid derivatives and process for preparing the same | 厦门华厦学院 | 2021-12-03 | — | — | CN | disclosed |
| CN-109651179-A | 2- (2- amino benzoyl) benzoic acid derivative and preparation method thereof | 厦门华厦学院 | 2019-04-19 | — | — | CN | disclosed |