Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 7/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30282651 | 1.00 | SIRT1 (0.44) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL28659051 | 0.99 | SIRT1 (0.43) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL28654122 | 0.99 | SIRT1 (0.43) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL6883142 | 0.91 | DVL1 (0.35) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL30282777 | 0.88 | SIRT1 (0.42) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL30282721 | 0.88 | SIRT1 (0.42) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL28655392 | 0.88 | SIRT1 (0.42) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL28649772 | 0.88 | SIRT1 (0.44) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL30282855 | 0.88 | SIRT1 (0.44) | SIRT1RARBMEN1KMT2AATM | |
| SCHEMBL30282731 | 0.87 | MEN1 (0.50) | SIRT1MEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717091-B | Indole derivatives and preparation method and application thereof | 南京医科大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-113717091-A | Indole derivatives and preparation method and application thereof | 南京医科大学 | 2021-11-30 | — | — | CN | disclosed |