SCHEMBL28655481

SCHEMBL28655481

C[Si](C)(C)OCCOC(N)=O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
CHRM2 P08172 2/20 0.46
CHRM4 P08173 2/20 0.46
CHRM5 P08912 2/20 0.46
CHRM1 P11229 2/20 0.46
CHRM3 P20309 2/20 0.46
CHRNB2 P17787 2/20 0.46
CHRNA4 P43681 2/20 0.46
HTR1A P08908 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46
CHRNA7 P36544 1/20 0.46
ALOX15 P16050 1/20 0.44
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
HSD17B10 Q99714 1/20 0.33
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2547540 0.79 LMNA (0.57) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL23461816 0.79 LMNA (0.41) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL30525718 0.76 LMNA (0.62) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL29245838 0.76 CHRNB2 (0.46) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL16197570 0.74 DUT (0.39) LMNACHRM2CHRM4CHRM5CHRM1
Ethylene SCHEMBL21679941 0.73 TSHR (0.52) LMNACHRM2CHRM4CHRM5CHRM1
Formaldehyde SCHEMBL4454552 0.73 TSHR (0.52) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL78042 0.73 LMNA (0.48) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL29610858 0.73 LMNA (0.48) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL28944802 0.73 KMT2A (0.30) CYP2C19ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113549309-A Low-cost biodegradable film and preparation method thereof 安徽瑞鸿新材料科技有限公司 2021-10-26 CN disclosed