SCHEMBL28655713

SCHEMBL28655713

CC(C#N)OC(=O)n1ccnc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
ESR1 P03372 1/20 0.40
CTSL P07711 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PLAA Q9Y263 1/20 0.34
GRM5 P41594 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
ALPG P10696 1/20 0.34
HDAC4 P56524 1/20 0.33
ABCC9 O60706 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
PORCN Q9H237 1/20 0.33
PDCD1 Q15116 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28414560 0.75 ALDH1A1 (0.42) ALDH1A1ESR1SMN1; SMN2
SCHEMBL15020446 0.74 TNK2 (0.45) ALDH1A1ESR1GRM5
SCHEMBL28848047 0.72 ESR1 (0.54) ALDH1A1ESR1KMT2ASMN1; SMN2PLAA
SCHEMBL11078694 0.72 ESR1 (0.54) ALDH1A1ESR1KMT2ASMN1; SMN2PLAA
SCHEMBL9880609 0.70 ESR1 (0.47) ALDH1A1ESR1KMT2AMEN1SMN1; SMN2
Mellitic Acid SCHEMBL28628589 0.70 ESR1 (0.41) ESR1CTSLCTSSCTSKKMT2A
SCHEMBL10668273 0.70 ESR1 (0.51) ALDH1A1ESR1KMT2APLAAADORA2A
SCHEMBL28035198 0.69 ESR1 (0.51) ESR1GAASMN1; SMN2PLAAALPG
SCHEMBL84081 0.69 BRD4 (0.41) ALDH1A1ESR1KMT2AABCC9MAPT
SCHEMBL425549 0.69 SMN1; SMN2 (0.52) ALDH1A1ESR1KMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748586-A Sheet material for producing electromagnetic components, in particular stator cores or rotor cores, and method for producing electromagnetic components 蒂森克虏伯钢铁欧洲股份公司 2021-12-03 CN disclosed