SCHEMBL187244

SCHEMBL187244

OCc1ccc2ncccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.57
POLB P06746 2/20 0.57
RAB9A P51151 1/20 0.57
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
HTT P42858 2/20 0.53
KDM4E B2RXH2 1/20 0.53
TP53 P04637 1/20 0.53
HSP90AA1 P07900 1/20 0.53
HSP90AB1 P08238 1/20 0.53
TSHR P16473 1/20 0.53
CASP1 P29466 1/20 0.53
ATM Q13315 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
HSD17B10 Q99714 1/20 0.53
DAO P14920 1/20 0.52
HDAC3 O15379 2/20 0.50
MET P08581 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9256396 0.98 NPC1 (0.55) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL7528128 0.86 NPC1 (0.70) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL252567 0.85 DAO (0.54) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL2865593 0.85 ALDH1A1 (0.58) NPC1POLBRAB9AALDH1A1HTT
SCHEMBL19283123 0.83 ALDH1A1 (0.56) NPC1POLBRAB9AALDH1A1HTT
Ammonia Solution, Strong SCHEMBL27721873 0.83 ALDH1A1 (0.56) NPC1POLBRAB9AALDH1A1HTT
SCHEMBL3158800 0.82 DAO (0.51) NPC1POLBRAB9AALDH1A1MAPT
Ethane SCHEMBL9847468 0.81 ALDH1A1 (0.55) RAB9AALDH1A1HTTTP53CASP1
SCHEMBL2107923 0.81 NPC1 (0.57) NPC1POLBRAB9AALDH1A1MAPT
SCHEMBL4075213 0.81 NPC1 (0.57) NPC1POLBRAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124609-A1 PREPARATION METHOD OF DUAL-ANION CATALYST, AND USE OF DUAL-ANION CATALYST IN CATALYTIC DEGRADATION OF POLYURETHANE MATERIAL ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2026-05-07 US claimed
CN-116713034-B Organic photocatalyst, preparation method and method for preparing oxo-isophorone by using organic photocatalyst 万华化学集团股份有限公司 2025-06-03 CN claimed
CN-116943730-B Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound 浙江大学 2025-04-11 CN claimed
CN-119303631-A Preparation method of dianion catalyst and application of dianion catalyst in catalytic degradation of polyurethane material 浙江工业大学 2025-01-14 CN claimed
CN-113559904-B Application of nitrogen-carbon material anchored iron single-atom catalyst in catalyzing ammoxidation of alcohol to prepare nitrile 南京理工大学 2024-04-02 CN claimed
CN-116943730-A Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound 浙江大学 2023-10-27 CN claimed
CN-116713034-A Organic photocatalyst, preparation method and method for preparing oxo-isophorone by using organic photocatalyst 万华化学集团股份有限公司 2023-09-08 CN claimed
CN-113559904-A Application of nitrogen-carbon material anchored iron monatomic catalyst in reaction for catalyzing ammoxidation of alcohol to prepare nitrile 南京理工大学 2021-10-29 CN claimed
US-5459150-A Treatment of allergies and inflammatory diseases ABBOTT LABORATORIES (US) 1995-10-17 US claimed
US-20260124609-A1 PREPARATION METHOD OF DUAL-ANION CATALYST, AND USE OF DUAL-ANION CATALYST IN CATALYTIC DEGRADATION OF POLYURETHANE MATERIAL ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2026-05-07 US disclosed
CN-116713034-B Organic photocatalyst, preparation method and method for preparing oxo-isophorone by using organic photocatalyst 万华化学集团股份有限公司 2025-06-03 CN disclosed
CN-116943730-B Method for preparing cyclic amine compound by catalyzing hydrogenation of pyridine and quinoline compound 浙江大学 2025-04-11 CN disclosed
CN-116102483-B Substituted pyrrole-2, 5-diketone compound and preparation method and application thereof 中国医学科学院药物研究所 2025-01-17 CN disclosed
CN-119303631-A Preparation method of dianion catalyst and application of dianion catalyst in catalytic degradation of polyurethane material 浙江工业大学 2025-01-14 CN disclosed
EP-0381375-A1 Heterocyclic derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-08-08 EP disclosed
EP-0371564-A2 (1H-azol-1-ylmethyl)substituted quinoline, quinazoline or quinoxaline derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1990-06-06 EP disclosed
CN-1035501-A PROCESS FOR PREPARING SUBSTITUTED QUINOLINE DERIVATIVES SMITHKLINE BECKMAN INTERCREDIT (NL) 1989-09-13 CN disclosed
US-4734407-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1988-03-29 US disclosed
EP-0197294-A2 Beta-lactam antibiotics, process for their preparation and their use as medicaments BAYER AG (DE) 1986-10-15 EP disclosed
CN-86101695-A Prepare the method for β-Nei Xiananleikangshengsu and the application in medicine thereof 1986-09-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124609-A1 PREPARATION METHOD OF DUAL-ANION CATALYST, AND USE OF DUAL-ANION CATALYST IN CATALYTIC DEGRADATION OF POLYURETHANE MATERIAL SOD1, DUOX2, JMJD6 NPC1 4077/4885POLB 363/4885RAB9A 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.