SCHEMBL2865616

SCHEMBL2865616

Cc1[c]ccc(C(C)(C)c2ccc(C(C)(C)c3cc[c]c(C)c3)cc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
ESR2 Q92731 3/20 0.41
CYP3A4 P08684 3/20 0.39
TSHR P16473 3/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
AR P10275 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ALOX15 P16050 2/20 0.36
ALOX12 P18054 2/20 0.36
ALDH1A1 P00352 2/20 0.34
KLF10 Q13118 1/20 0.34
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
RORC P51449 1/20 0.32
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580414 0.96 ESR1 (0.41) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL2869063 0.82 TSHR (0.39) TSHRHPGDHSD17B10ALOX15ALDH1A1
SCHEMBL3945118 0.78 ESR1 (0.30) ESR1
SCHEMBL8782236 0.77
SCHEMBL95846 0.76 KIF11 (0.36) TSHRALDH1A1
SCHEMBL11817162 0.74 SHBG (0.42) ESR1CYP3A4TSHRARSLC6A2
SCHEMBL699200 0.72
SCHEMBL7571742 0.71 ESR1 (0.35) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL11502201 0.71 ESR1 (0.45) ESR1ESR2CYP3A4TSHRHPGD
SCHEMBL4470598 0.71 ESR1 (0.35) ESR1ESR2CYP3A4TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed