SCHEMBL4580414

SCHEMBL4580414

Cc1[c]ccc(C(C)(C)c2cc[c]c(C)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.41
ESR2 Q92731 2/20 0.34
ALOX15 P16050 2/20 0.34
ALOX12 P18054 2/20 0.34
CYP3A4 P08684 2/20 0.33
HPGD P15428 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CASP1 P29466 1/20 0.33
RECQL P46063 1/20 0.33
HIF1A Q16665 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KLF10 Q13118 1/20 0.32
AR P10275 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
HTR6 P50406 1/20 0.32
ESRRG P62508 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865616 0.96 ESR1 (0.43) ESR1ESR2ALOX15ALOX12CYP3A4
SCHEMBL2869063 0.86 TSHR (0.39) ALOX15HPGDTSHRHSD17B10ALDH1A1
SCHEMBL3945118 0.82 ESR1 (0.30) ESR1
SCHEMBL8782236 0.80
SCHEMBL95846 0.79 KIF11 (0.36) TSHRALDH1A1
SCHEMBL11817162 0.77 SHBG (0.42) ESR1CYP3A4TSHRALDH1A1CASP1
SCHEMBL699200 0.76
SCHEMBL7571742 0.74 ESR1 (0.35) ESR1ESR2ALOX15ALOX12CYP3A4
SCHEMBL11502201 0.74 ESR1 (0.45) ESR1ESR2ALOX15ALOX12CYP3A4
SCHEMBL4470598 0.74 ESR1 (0.35) ESR1ESR2ALOX15ALOX12CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1900541-B1 Heat-sensitive recording material and production method thereof RICOH CO LTD (JP) 2014-08-13 EP disclosed
US-7906458-B2 Color developing layer on a substrate, containing a leuco dye and a developer; protective layer of a binder resin, of diacetone-modified polyvinyl alcohol resin RICOH COMPANY, LTD. (JP) 2011-03-15 US disclosed
US-20080146443-A1 Heat-sensitive recording material and production method thereof RICOH COMPANY, LTD. (JP) 2008-06-19 US disclosed
EP-1900541-A1 Heat-sensitive recording material and production method thereof RICOH Co., Ltd. (JP) 2008-03-19 EP disclosed
US-4355823-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1982-10-26 US disclosed
US-4316036-A COLOR-FORMERS IN RECORDING MATERIAL CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4291902-A PRESSURE- AND HEAT-SENSITIVE ELEMENTS; COPYING; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1981-09-29 US disclosed
US-4238130-A Pressure-sensitive or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1980-12-09 US disclosed
US-4191690-A COLOR FORMERS CIBA-GEIGY CORPORATION (US) 1980-03-04 US disclosed