Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 6/20 | 0.47 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfacetamide SCHEMBL28653550 | 0.88 | SMN1; SMN2 (0.78) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL15650208 | 0.81 | ALDH1A1 (0.69) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL4464537 | 0.79 | CA1 (0.70) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL5458800 | 0.78 | ALDH1A1 (0.65) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL29289293 | 0.77 | TSHR (0.42) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL28405273 | 0.76 | EGFR (0.60) | TSHRSMN1; SMN2TDP1ALDH1A1CA1 | |
| SCHEMBL21082820 | 0.76 | ALDH1A1 (0.61) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| Sulfacetamide SCHEMBL28122264 | 0.76 | SMN1; SMN2 (1.00) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| Sulfacetamide SCHEMBL40863 | 0.76 | SMN1; SMN2 (1.00) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL3146545 | 0.75 | ALDH1A1 (0.60) | DHFRTSHRSMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861083-A | Preparation method of acetoacetyl sulfanilamide triethylamine salt | 南通醋酸化工股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113861083-A | Preparation method of acetoacetyl sulfanilamide triethylamine salt | 南通醋酸化工股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861083-A | Preparation method of acetoacetyl sulfanilamide triethylamine salt | 南通醋酸化工股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113861083-A | Preparation method of acetoacetyl sulfanilamide triethylamine salt | 南通醋酸化工股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113788802-A | Method for preparing acesulfame potassium | 南通醋酸化工股份有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-113563284-A | Preparation method of acesulfame potassium composition | 南通醋酸化工股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113563283-A | Preparation method of acesulfame potassium composition | 南通醋酸化工股份有限公司 | 2021-10-29 | — | — | CN | disclosed |