Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165528 | 0.84 | SMN1; SMN2 (0.60) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL15650208 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL3152558 | 0.81 | KMT2A (0.62) | ALDH1A1TDP1KMT2ALMNAMEN1 | |
| SCHEMBL23703133 | 0.80 | KMT2A (0.73) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL5458800 | 0.80 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL4464537 | 0.77 | CA1 (0.70) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL21082820 | 0.77 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL3152499 | 0.77 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 | |
| SCHEMBL11429211 | 0.76 | TSHR (0.69) | ALDH1A1SMN1; SMN2TSHRTDP1KMT2A | |
| SCHEMBL8198870 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2DHFRTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313699-B1 | 5-ASA DERIVATIVES HAVING ANTI-INFLAMMATORY AND ANTIBIOTIC ACTIVITY AND METHODS OF TREATING DISEASES THEREWITH | BIOCON LTD (IN) | 2010-03-10 | — | — | EP | disclosed |
| EP-1313699-A1 | 5-ASA DERIVATIVES HAVING ANTI-INFLAMMATORY AND ANTIBIOTIC ACTIVITY AND METHODS OF TREATING DISEASES THEREWITH | Nobex Corporation (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6458776-B1 | INFLAMMATORY BOWEL DISEASE | NOBEX CORPORATION | 2002-10-01 | — | — | US | disclosed |
| US-20020111334-A1 | 5-ASA derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith | BIOCON LIMITED (IN) | 2002-08-15 | — | — | US | disclosed |
| WO-2002018330-A1 | 5-ASA DERIVATIVES HAVING ANTI-INFLAMMATORY AND ANTIBIOTIC ACTIVITY AND METHODS OF TREATING DISEASES THEREWITH | NOBEX CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111334-A1 | 5-ASA derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith | SLC30A5, SI, ABCB11 | ALDH1A1 164/4885SMN1; SMN2 1755/4885DHFR 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.