Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.45 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222146 | 0.85 | KAT6A (0.57) | KAT6AKMOSRPK1RPS6KB2KDM4E | |
| SCHEMBL940399 | 0.85 | KAT6A (0.57) | KAT6AKMOSRPK1RPS6KB2KDM4E | |
| SCHEMBL9637810 | 0.78 | PTPN1 (0.48) | KAT6ASRPK1RPS6KB2DAOKDM4E | |
| SCHEMBL3915007 | 0.78 | TPMT (0.50) | KAT6ASRPK1RPS6KB2DHODHKDM4E | |
| Benzoic Acid SCHEMBL26966093 | 0.77 | DAO (0.54) | KAT6AKMODAOKDM4EMAPT | |
| SCHEMBL27623947 | 0.76 | KAT6A (0.55) | KAT6AHDAC1HDAC3HDAC2HTR1A | |
| SCHEMBL27905638 | 0.75 | KAT6A (0.58) | KAT6AKMOHDAC1HDAC3HDAC2 | |
| SCHEMBL938500 | 0.74 | KMO (0.52) | KMODAODHODHKDM4EMEN1 | |
| SCHEMBL420705 | 0.74 | KDM4E (0.55) | SRPK1RPS6KB2DAOKDM4EMAPT | |
| SCHEMBL6040460 | 0.74 | KAT6A (0.47) | KAT6AKMOSRPK1RPS6KB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976172-B | 4-pyrimidinediamine micromolecule organic compound and derivative and application thereof | 华东师范大学 | 2021-12-07 | — | — | CN | disclosed |