Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 2/20 | 0.54 |
| ▸ | BCR | P11274 | 2/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.50 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL26966093 | 0.90 | DAO (0.54) | KDM4EMAPTEGLN1HDAC2HPGDS | |
| SCHEMBL4727765 | 0.87 | KDM4E (0.46) | KDM4EMAPTABL1BCREGLN1 | |
| SCHEMBL27605045 | 0.86 | ABL1 (0.55) | KDM4EABL1BCRLTA4HHDAC2 | |
| SCHEMBL3283049 | 0.85 | HPGDS (0.56) | MAPTABL1BCRLTA4HHDAC2 | |
| SCHEMBL27889063 | 0.85 | CES2 (0.56) | ABL1BCRLTA4HHDAC2HPGDS | |
| SCHEMBL6040819 | 0.83 | TNFRSF1A (0.65) | MAPTHDAC2TP53PTPN1ALOX15 | |
| SCHEMBL4727769 | 0.83 | TNFRSF1A (0.65) | MAPTHDAC2TP53PTPN1ALOX15 | |
| SCHEMBL6040823 | 0.83 | TNFRSF1A (0.65) | MAPTHDAC2TP53PTPN1ALOX15 | |
| SCHEMBL4727774 | 0.83 | TNFRSF1A (0.65) | MAPTHDAC2TP53PTPN1ALOX15 | |
| SCHEMBL940399 | 0.83 | KAT6A (0.57) | KDM4EMAPTSRPK1RPS6KB2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992307-A | BIS-PHOSPHORAMIDE | CHEVRON RESEARCH COMPANY (US) | 1976-11-16 | — | — | US | claimed |
| US-20250353833-A1 | DPP9 BINDING COMPOUNDS | UNIV ANTWERPEN (BE) | 2025-11-20 | — | — | US | disclosed |
| EP-4405334-B1 | SORTILIN INHIBITORS | SORTINA PHARMA AB (SE) | 2025-02-12 | — | — | EP | disclosed |
| US-20250002460-A1 | SORTILIN INHIBITORS | SORTINA PHARMA AB (SE) | 2025-01-02 | — | — | US | disclosed |
| CN-118496135-B | Thiourea compound or pharmaceutically acceptable salt thereof and application thereof as immunosuppressant | 中国海洋大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118496135-A | Thiourea compound or pharmaceutically acceptable salt thereof and application thereof as immunosuppressant | 中国海洋大学 | 2024-08-16 | — | — | CN | disclosed |
| EP-4405334-A1 | SORTILIN INHIBITORS | Sortina Pharma AB (SE) | 2024-07-31 | — | — | EP | disclosed |
| US-20240228471-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | UNIVERSITEIT ANTWERPEN (BE) | 2024-07-11 | — | — | US | disclosed |
| CN-118317947-A | Sortilin inhibitors | 索蒂纳制药股份有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-115872947-B | Benzisothiazole benzamide compound or pharmaceutically acceptable salt thereof, preparation method and application | 中国药科大学 | 2024-04-19 | — | — | CN | disclosed |
| WO-2000037592-A1 | NON-SLUDGING, HIGH TEMPERATURE RESISTANT FOOD COMPATIBLE LUBRICANT FOR FOOD PROCESSING MACHINERY | EXXON RESEARCH & ENGINEERING COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |
| US-5849735-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| CN-1190391-A | Tricyclic benzazepine vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-08-12 | — | — | CN | disclosed |
| EP-0804420-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| CN-1017708-B | METHOD FOR PREPARATION OF PYRAZOLOTRIAZINE COMPOUNDS | OTSUKA CHEMICAL CO LTD (JP) | 1992-08-05 | — | — | CN | disclosed |
| CN-87107217-A | Method for preparation of pyrazolotriazine compounds | — | 1988-05-11 | — | — | CN | disclosed |
| US-4088587-A | ANTIOXIDANT AND PHOSPHORUS-CONTAINING COMPOSITION | CHEVRON RESEARCH COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4032462-A | AN ANTIOXIDANT AND AN ORGANO-ANTIMONY COMPOUND | CHEVRON RESEARCH COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-3958624-A | Heat transfer fluids | CHEVRON RESEARCH COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002460-A1 | SORTILIN INHIBITORS | SORT1, GRN, SCARB1 | KDM4E 4845/4885MAPT 367/4885ABL1 3945/4885 |
| US-20250353833-A1 | DPP9 BINDING COMPOUNDS | DPP9, DPP7, DPP3 | KDM4E 1503/4885MAPT 2577/4885ABL1 1380/4885 |
| US-20240228471-A1 | MOF, MOF LINKERS AND MANUFACTURING METHOD THEREOF | ILK, MTCL3, FTO | KDM4E 146/4885MAPT 1349/4885ABL1 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.