Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Tert-Butylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.45 |
| ▸ | PGK2 | P07205 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylbenzene SCHEMBL6285328 | 1.00 | PTPN1 (0.54) | PTPN1RAB9ALMNAMAPTKMT2A | |
| Tert-Butylbenzene SCHEMBL27361324 | 1.00 | PTPN1 (0.54) | PTPN1RAB9ALMNAMAPTKMT2A | |
| Tert-Butylbenzene SCHEMBL29208969 | 1.00 | PTPN1 (0.54) | PTPN1RAB9ALMNAMAPTKMT2A | |
| Tert-Butylbenzene SCHEMBL309340 | 0.87 | LMNA (0.55) | RAB9ALMNAMAPTKMT2ATDP1 | |
| Tert-Butylbenzene SCHEMBL27449728 | 0.84 | MAPT (0.56) | RAB9ALMNAMAPTKMT2AKCNK9 | |
| Tert-Butylbenzene SCHEMBL28457869 | 0.84 | LMNA (0.52) | RAB9ALMNAMAPTKMT2ATDP1 | |
| Tert-Butylbenzene SCHEMBL27300848 | 0.84 | LMNA (0.52) | RAB9ALMNAMAPTKMT2ATDP1 | |
| Tert-Butylbenzene SCHEMBL22264597 | 0.84 | MAPK1 (0.55) | LMNAMAPTKMT2ATDP1L3MBTL1 | |
| Tert-Butylbenzene SCHEMBL22264599 | 0.84 | MAPK1 (0.55) | LMNAMAPTKMT2ATDP1L3MBTL1 | |
| Tert-Butylbenzene SCHEMBL337648 | 0.84 | MAPK1 (0.55) | LMNAMAPTKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138995-B | Battery cell isolation buffer adhesive tape and application thereof | 苏州赛伍应用技术股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-111073571-B | Adhesive, packaging tape containing adhesive and application of packaging tape | 苏州赛伍应用技术股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114058278-A | High-temperature-resistant insulating adhesive film and preparation method and application thereof | 苏州赛伍应用技术股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113717676-A | Flame-retardant hot melt adhesive, flame-retardant hot melt adhesive film and flexible wire rod | 深圳市睿晖新材料有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-107586518-B | Photovoltaic module busbar insulating tape, busbar and photovoltaic module containing same | 苏州赛伍应用技术股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112760070-A | Insulation adhesive film for flexible flat cable and preparation method thereof | 苏州赛伍应用技术股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111138995-A | Battery cell isolation buffer adhesive tape and application thereof | 苏州赛伍应用技术股份有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-111073571-A | Adhesive, packaging tape containing adhesive and application of packaging tape | 苏州赛伍应用技术股份有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-107629713-B | Photovoltaic module busbar insulating tape, busbar and photovoltaic module containing same | 苏州赛伍应用技术股份有限公司 | 2020-03-24 | — | — | CN | disclosed |