SCHEMBL28656281

SCHEMBL28656281

Nc1ccc(N(C=O)C2CCCCC2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 9/20 0.39
ADH1C P00326 6/20 0.38
ADH4 P08319 1/20 0.36
ADH1B P00325 1/20 0.35
EPHX1 P07099 2/20 0.35
RAB9A P51151 2/20 0.35
GAA P10253 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
NFE2L2 Q16236 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.32
KDM4E B2RXH2 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4118370 0.82 CYP2C9 (0.40) ADH1AADH1CADH4ADH1BEPHX1
SCHEMBL14855822 0.81 TRPM8 (0.46) ADH1AADH1CADH4ADH1BRAB9A
SCHEMBL3245978 0.81 TRPM8 (0.46) ADH1AADH1CADH4ADH1BRAB9A
SCHEMBL28241420 0.80 PARP10 (0.44) ADH1AALOX15KDM4EMEN1KMT2A
SCHEMBL14855772 0.79 TRPM8 (0.44) ADH1AADH1CADH4RAB9AALDH1A1
SCHEMBL15703600 0.79 ADH1A (0.39) ADH1AADH1CADH4ADH1BRAB9A
SCHEMBL14855593 0.77 TRPM8 (0.41) ADH1AADH1CADH4RAB9AALDH1A1
SCHEMBL3692131 0.75 ALDH1A1 (0.39) EPHX1RAB9AGAAALDH1A1CYP3A4
SCHEMBL3698294 0.75 ALDH1A1 (0.39) EPHX1RAB9AGAAALDH1A1CYP3A4
SCHEMBL39105 0.75 ALDH1A1 (0.39) EPHX1RAB9AGAAALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113621175-B Efficient isotactic polypropylene beta-crystal form nucleating agent and preparation method and application thereof 中国科学院化学研究所 2022-10-18 CN disclosed
CN-113621175-A Efficient isotactic polypropylene beta-crystal form nucleating agent and preparation method and application thereof 中国科学院化学研究所 2021-11-09 CN disclosed