Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 13/20 | 0.66 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656105 | 0.85 | BCL6 (0.60) | BCL6NCOR2ROCK2ROCK1 | |
| SCHEMBL28661657 | 0.84 | BCL6 (0.79) | BCL6NCOR2ROCK2 | |
| SCHEMBL28671690 | 0.84 | BCL6 (0.76) | BCL6NCOR2ROCK2 | |
| SCHEMBL28671666 | 0.83 | BCL6 (0.73) | BCL6NCOR2ROCK2ROCK1 | |
| SCHEMBL20774579 | 0.82 | ROCK2 (0.80) | BCL6NCOR2ROCK2ROCK1 | |
| SCHEMBL30979645 | 0.80 | SYK (0.58) | BCL6ROCK2ROCK1SYK | |
| SCHEMBL28661662 | 0.76 | BCL6 (0.73) | BCL6NCOR2ROCK2 | |
| SCHEMBL28675624 | 0.76 | BCL6 (0.70) | BCL6NCOR2ROCK2 | |
| SCHEMBL28677146 | 0.76 | BCL6 (0.62) | BCL6NCOR2 | |
| SCHEMBL28656470 | 0.74 | BCL6 (0.69) | BCL6NCOR2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976172-B | 4-pyrimidinediamine micromolecule organic compound and derivative and application thereof | 华东师范大学 | 2021-12-07 | — | — | CN | disclosed |