Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.54 |
| ▸ | BCL6 | P41182 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656366 | 0.80 | BCL6 (0.66) | SYKROCK2ROCK1BCL6 | |
| SCHEMBL17547519 | 0.79 | ULK1 (0.53) | SYKROCK2ROCK1BCL6 | |
| SCHEMBL657089 | 0.74 | SYK (1.00) | SYKAURKA | |
| SCHEMBL23867516 | 0.74 | POLB (0.53) | BCL6PDE4B | |
| SCHEMBL10187339 | 0.74 | KDM4E (0.47) | PIK3CA | |
| SCHEMBL31513695 | 0.74 | KDM4E (0.47) | PIK3CA | |
| SCHEMBL22909158 | 0.73 | SYK (0.69) | SYKBCL6AURKA | |
| SCHEMBL4937858 | 0.73 | SYK (0.97) | SYKAURKA | |
| Hydrochloric Acid SCHEMBL655563 | 0.73 | SYK (0.97) | SYKAURKA | |
| SCHEMBL23867510 | 0.72 | HRH3 (0.52) | ROCK2ROCK1BCL6HTR2CAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118338898-A | Small molecule inhibitors of oncogenic CHD1L with preclinical anti-colorectal cancer activity | 科罗拉多州立大学董事会（法人团体） | 2024-07-12 | — | — | CN | disclosed |