Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | MAPK15 | Q8TD08 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655477 | 0.90 | ABL1 (0.51) | SMN1; SMN2GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL28655500 | 0.85 | NTRK1 (0.50) | SMN1; SMN2MAPTKDM4EALDH1A1ABL1 | |
| SCHEMBL182131 | 0.79 | MEN1 (0.54) | ABL1BCRNPC1RAB9A | |
| SCHEMBL19902125 | 0.76 | NPC1 (0.46) | L3MBTL1ABL1BCRNPC1RAB9A | |
| SCHEMBL28669052 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2MAPTKDM4EALDH1A1FYN | |
| SCHEMBL28668115 | 0.75 | LMNA (0.49) | MAPTALDH1A1PKMABL1BCR | |
| SCHEMBL28658953 | 0.74 | NTRK1 (0.48) | MAPTALDH1A1MAPK1ABL1BCR | |
| SCHEMBL28661013 | 0.73 | FGFR3 (0.53) | SMN1; SMN2MAPTKDM4EALDH1A1FYN | |
| SCHEMBL182148 | 0.72 | BCL2L1 (0.49) | SMN1; SMN2GAAKDM4EMAPK1ABL1 | |
| SCHEMBL28656138 | 0.72 | ABL1 (0.49) | SMN1; SMN2MAPTKDM4EALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |