Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969633 | 0.69 | MAOA (0.41) | KMT2A | |
| SCHEMBL29614071 | 0.69 | MAOA (0.41) | KMT2A | |
| Hydrochloric Acid SCHEMBL30423571 | 0.67 | MAOA (0.39) | KMT2A | |
| SCHEMBL30219773 | 0.67 | KMT2A (0.35) | KMT2ABRD4BRD2 | |
| SCHEMBL15509629 | 0.65 | CHRM2 (0.37) | BRD4BRD2 | |
| SCHEMBL31292622 | 0.65 | POLB (0.43) | KMT2ABRD4BRD2 | |
| SCHEMBL29497244 | 0.65 | KMT2A (0.32) | KMT2A | |
| SCHEMBL261177 | 0.64 | — | — | |
| SCHEMBL3626737 | 0.63 | KDM4E (0.38) | KMT2ABRD4BRD2 | |
| SCHEMBL31437048 | 0.63 | CHRNB2 (0.34) | BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490495-A | Small molecule degradation agent of HELIOS and use method thereof | 达纳-法伯癌症研究公司 | 2021-10-08 | — | — | CN | disclosed |