Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832123 | 1.00 | OPRM1 (0.34) | OPRM1POLBNPSR1PGR | |
| SCHEMBL13440545 | 0.71 | NOTUM (0.40) | POLBNPSR1 | |
| SCHEMBL19181866 | 0.69 | KCNH2 (0.33) | — | |
| SCHEMBL19179761 | 0.69 | KCNH2 (0.33) | — | |
| SCHEMBL30995171 | 0.67 | CYP11B2 (0.38) | OPRM1 | |
| SCHEMBL19181084 | 0.66 | KCNH2 (0.36) | — | |
| SCHEMBL19179898 | 0.64 | POLB (0.32) | POLBNPSR1 | |
| SCHEMBL30995121 | 0.64 | DGAT1 (0.31) | — | |
| SCHEMBL19194951 | 0.63 | TOP2A (0.32) | — | |
| SCHEMBL19181099 | 0.63 | KCNH2 (0.33) | OPRM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767106-B | Oxazaquinazolin-7 (8H) -ones, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-3964516-A1 | OXAAZAQUINAZOLINE-7(8H)-KETONE COMPOUND, PREPARATION METHOD THERFOR AND PHARMACEUTICAL APPLICATION THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2022-03-09 | — | — | EP | disclosed |
| CN-113767106-A | Oxaazaquinazolin-7 (8H) -ones, their preparation and pharmaceutical use | 劲方医药科技(上海)有限公司 | 2021-12-07 | — | — | CN | disclosed |