Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | SNCA | P37840 | 9/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CDK4 | P11802 | 1/20 | 0.62 |
| ▸ | CCND1 | P24385 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18856136 | 0.86 | SNCA (0.78) | MAPTSMN1; SMN2SNCAMTNR1AMTNR1B | |
| SCHEMBL9936095 | 0.85 | CDK4 (0.78) | MAPTSMN1; SMN2SNCAMTNR1AMTNR1B | |
| SCHEMBL9938370 | 0.83 | SNCA (0.81) | SNCA | |
| SCHEMBL15150099 | 0.83 | MTNR1A (0.68) | MAPTSMN1; SMN2SNCAMTNR1AMTNR1B | |
| SCHEMBL15313143 | 0.83 | SNCA (1.00) | SNCA | |
| SCHEMBL28638898 | 0.81 | PTGS2 (0.72) | MAPTSMN1; SMN2SNCAMTNR1AMTNR1B | |
| SCHEMBL31543697 | 0.80 | MTNR1A (1.00) | MAPTSMN1; SMN2MTNR1AMTNR1BGAA | |
| SCHEMBL1771902 | 0.80 | MTNR1A (1.00) | MAPTSMN1; SMN2MTNR1AMTNR1BGAA | |
| SCHEMBL9934805 | 0.80 | SNCA (0.84) | MAPTSNCASIRT1CDK4CCND1 | |
| SCHEMBL18856056 | 0.79 | MAPT (0.57) | MAPTSMN1; SMN2SNCAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563250-A | Benzoic acid tryptamine derivative and preparation and application thereof | 南华大学 | 2021-10-29 | — | — | CN | disclosed |