Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645900 | 0.98 | ALDH1A1 (0.48) | HSD17B10ALDH1A1PRKDCERCC1DNASE1 | |
| SCHEMBL28651740 | 0.97 | HSD17B10 (0.43) | HSD17B10ALDH1A1PRKDCERCC1DNASE1 | |
| SCHEMBL28661113 | 0.86 | PRKDC (0.40) | ALDH1A1PRKDCMAPTKMT2AKDM4E | |
| SCHEMBL28637400 | 0.82 | ALDH1A1 (0.57) | HSD17B10ALDH1A1PRKDCERCC1DNASE1 | |
| SCHEMBL22501691 | 0.82 | KDM4E (0.54) | HSD17B10ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL24589799 | 0.81 | MAOB (0.55) | HSD17B10ALDH1A1PRKDCMAPTL3MBTL1 | |
| SCHEMBL1937101 | 0.79 | HSD17B10 (0.53) | HSD17B10ALDH1A1PRKDCERCC1DNASE1 | |
| SCHEMBL32677438 | 0.79 | HSD17B10 (0.53) | HSD17B10ALDH1A1PRKDCERCC1DNASE1 | |
| SCHEMBL18493216 | 0.79 | ALDH1A1 (0.54) | HSD17B10ALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL1937493 | 0.78 | HSD17B10 (0.51) | HSD17B10ALDH1A1PRKDCERCC1DNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593084-B | Prolyl hydroxylase small-molecule photosensitive prodrug and preparation method and application thereof | 中国药科大学 | 2021-09-28 | — | — | CN | claimed |