Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656942 | 0.98 | HSD17B10 (0.46) | ALDH1A1PRKDCHSD17B10ERCC1DNASE1 | |
| SCHEMBL28651740 | 0.95 | HSD17B10 (0.43) | ALDH1A1PRKDCHSD17B10ERCC1DNASE1 | |
| SCHEMBL28661113 | 0.85 | PRKDC (0.40) | ALDH1A1PRKDCMAPTKMT2AGAA | |
| SCHEMBL24589799 | 0.82 | MAOB (0.55) | ALDH1A1PRKDCHSD17B10MAPTL3MBTL1 | |
| SCHEMBL22501691 | 0.81 | KDM4E (0.54) | ALDH1A1HSD17B10MAPTL3MBTL1MAOB | |
| SCHEMBL28637400 | 0.81 | ALDH1A1 (0.57) | ALDH1A1PRKDCHSD17B10ERCC1DNASE1 | |
| SCHEMBL1937493 | 0.80 | HSD17B10 (0.51) | ALDH1A1PRKDCHSD17B10ERCC1DNASE1 | |
| SCHEMBL28292847 | 0.79 | MCL1 (0.49) | ALDH1A1PRKDCHSD17B10MEN1MAPT | |
| SCHEMBL1937101 | 0.78 | HSD17B10 (0.53) | ALDH1A1PRKDCHSD17B10ERCC1DNASE1 | |
| SCHEMBL32677438 | 0.78 | HSD17B10 (0.53) | ALDH1A1PRKDCHSD17B10ERCC1DNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593084-B | Prolyl hydroxylase small-molecule photosensitive prodrug and preparation method and application thereof | 中国药科大学 | 2021-09-28 | — | — | CN | claimed |