SCHEMBL28657256

SCHEMBL28657256

CC1=C(CO[SiH3])c2cccc(C)c21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
HTR7 P34969 2/20 0.33
SCN4A P35499 3/20 0.31
LMNA P02545 2/20 0.31
SCN1A P35498 2/20 0.31
SCN5A Q14524 2/20 0.31
SCN9A Q15858 2/20 0.31
DAO P14920 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
KCNK3 O14649 1/20 0.31
CACNA1F O60840 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1315211 0.68 FFAR1 (0.36) MYCHTR7LMNACYP1A2CYP3A4
SCHEMBL4161420 0.65 CA1 (0.48) MYCCA1CA2CA7CA9
SCHEMBL2044927 0.65 CA1 (0.41) MYCCA1CA2CA7CA9
SCHEMBL106500 0.64 ESR1 (0.44) CA1CA2CA7CA9CYP1A2
SCHEMBL710879 0.63 TAAR1 (0.46) LMNATSHR
SCHEMBL3482557 0.63 CA12 (0.43) CA1CA2CA9HTR7GBA1
SCHEMBL28899579 0.62 MYC (0.58) MYCCA1CA2CA7CA9
SCHEMBL4819141 0.61 CA1 (0.38) MYCCA1CA2CA7CA9
SCHEMBL6263082 0.61 CA1 (0.47) MYCCA1CA2CA7CA9
SCHEMBL4021982 0.61 ACHE (0.57) MYCCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316271-A Linear benzocyclobutene polysiloxane resin 天诺光电材料股份有限公司 2022-04-12 CN disclosed
CN-113480735-A Benzocyclobutene-based functionalized organic silicon resin and preparation method thereof 天诺光电材料股份有限公司 2021-10-08 CN disclosed