SCHEMBL29134048

SCHEMBL29134048

COc1ccc(-c2oc3c(OC)c(OC)c(O)c(O)c3c(=O)c2OC)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.64
KDM4E B2RXH2 3/20 0.64
GAA P10253 2/20 0.64
TUBB4A P04350 2/20 0.62
TUBB P07437 2/20 0.62
TUBA3C P0DPH7 2/20 0.62
TUBA1B P68363 2/20 0.62
TUBA4A P68366 2/20 0.62
TUBB4B P68371 2/20 0.62
TUBB3 Q13509 2/20 0.62
TUBB2A Q13885 2/20 0.62
TUBB8 Q3ZCM7 2/20 0.62
TUBA3E Q6PEY2 2/20 0.62
TUBA1A Q71U36 2/20 0.62
TUBA1C Q9BQE3 2/20 0.62
TUBB6 Q9BUF5 2/20 0.62
TUBB2B Q9BVA1 2/20 0.62
TUBB1 Q9H4B7 2/20 0.62
CYP3A4 P08684 2/20 0.62
CYP2D6 P10635 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Hydroxyauranetin SCHEMBL4066374 0.95 MAPT (0.71) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL28998302 0.90 MAPT (0.63) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL22361649 0.89 MAPT (0.65) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL28655626 0.89 MAPT (0.65) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL30049379 0.86 MAPT (0.62) MAPTKDM4EGAATUBB4ATUBB
Calycopterin SCHEMBL2214965 0.85 KDM4E (0.73) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL28657635 0.85 MAPT (0.62) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL31558901 0.82 MAPT (0.85) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL4129003 0.82 MAPT (0.85) MAPTKDM4EGAATUBB4ATUBB
SCHEMBL1764438 0.82 ALDH1A1 (0.67) MAPTKDM4EGAATUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813017-A Method for improving intestinal microbiota diversity 雀巢产品有限公司 2024-04-02 CN disclosed
CN-116987550-A Spearmint spice and preparation method thereof 东莞市吉纯生物技术有限公司 2023-11-03 CN disclosed