SCHEMBL2216677

SCHEMBL2216677

COc1c(OC)c(O)c2c(=O)c(OC)c(-c3cccc(O)c3)oc2c1OC

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.70
GAA P10253 4/20 0.70
MAPT P10636 4/20 0.70
TUBB4A P04350 4/20 0.69
TUBB P07437 4/20 0.69
TUBA3C P0DPH7 4/20 0.69
TUBA1B P68363 4/20 0.69
TUBA4A P68366 4/20 0.69
TUBB4B P68371 4/20 0.69
TUBB3 Q13509 4/20 0.69
TUBB2A Q13885 4/20 0.69
TUBB8 Q3ZCM7 4/20 0.69
TUBA3E Q6PEY2 4/20 0.69
TUBA1A Q71U36 4/20 0.69
TUBA1C Q9BQE3 4/20 0.69
TUBB6 Q9BUF5 4/20 0.69
TUBB2B Q9BVA1 4/20 0.69
TUBB1 Q9H4B7 4/20 0.69
ALDH1A1 P00352 2/20 0.65
ABCB1 P08183 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31558901 0.87 MAPT (0.85) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL4129003 0.87 MAPT (0.85) KDM4EGAAMAPTTUBB4ATUBB
Calycopterin SCHEMBL2214965 0.84 KDM4E (0.73) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL28657635 0.84 MAPT (0.62) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL28996853 0.82 MAPT (0.60) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL507435 0.82 MAPT (1.00) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL7921852 0.81 TUBB4A (1.00) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL28980660 0.81 XDH (0.74) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL28652987 0.81 KDM4E (0.84) KDM4EGAAMAPTTUBB4ATUBB
SCHEMBL27969069 0.81 MAPT (0.85) KDM4EGAAMAPTTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115315195-B Hydroxy-and methoxy-substituted flavonoids and use thereof 弗门尼舍有限公司 2024-07-02 CN claimed
CN-115315195-A Hydroxy-and methoxy-substituted flavonoids and their use 弗门尼舍有限公司 2022-11-08 CN claimed
CN-115315195-B Hydroxy-and methoxy-substituted flavonoids and use thereof 弗门尼舍有限公司 2024-07-02 CN disclosed
CN-115315195-A Hydroxy-and methoxy-substituted flavonoids and their use 弗门尼舍有限公司 2022-11-08 CN disclosed
US-8557331-B2 Antifouling method and composition using chromen-4-one derivatives THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2013-10-15 US disclosed
US-20110177237-A1 ANTIFOULING METHOD AND COMPOSITION USING CHROMEN-4-ONE DERIVATIVES THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-07-21 US disclosed