Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21154729 | 0.83 | CYP3A4 (0.46) | THRBLMNAMAPTATMTSHR | |
| SCHEMBL22847742 | 0.74 | MAPT (0.40) | LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL431034 | 0.73 | ALDH1A1 (0.56) | LMNAMAPTDGKATSHRALDH1A1 | |
| SCHEMBL21919495 | 0.73 | KDM4E (0.42) | LMNAMAPTL3MBTL1GAANPSR1 | |
| SCHEMBL9764276 | 0.73 | ALDH1A1 (0.53) | PLA2G4BLMNAMAPTATML3MBTL1 | |
| SCHEMBL11401971 | 0.73 | NAAA (0.45) | EPHX2LMNAMAPTATML3MBTL1 | |
| SCHEMBL22303058 | 0.72 | ALDH1A1 (0.42) | LMNAMAPTL3MBTL1GAATSHR | |
| SCHEMBL9763783 | 0.70 | ATM (0.52) | PLA2G4BLMNAATMHTR2CNAAA | |
| SCHEMBL42383 | 0.69 | NAAA (0.62) | PLA2G4BHTR2CNAAADGKARAD52 | |
| SCHEMBL247153 | 0.69 | NAAA (0.62) | PLA2G4BHTR2CNAAADGKARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052866-B | Crystal form of nitrogen-containing heteroaromatic derivative free alkali | 上海翰森生物医药科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115052866-A | Crystal form of free base of nitrogen-containing heteroaromatic derivative | 上海翰森生物医药科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113493440-A | Salt of nitrogen-containing heteroaromatic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-111295374-A | Aza-containing aromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2020-06-16 | — | — | CN | disclosed |