Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434346 | 0.96 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL31497703 | 0.86 | LMNA (0.45) | ALDH1A1LMNATSHRTP53CYP3A4 | |
| SCHEMBL433166 | 0.85 | LMNA (0.74) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL432645 | 0.80 | LMNA (0.70) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL15927544 | 0.80 | LMNA (0.46) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9764276 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7864966 | 0.78 | LMNA (0.67) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL431027 | 0.78 | LMNA (0.67) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL433061 | 0.77 | PPARG (0.42) | LMNAKMT2ASMN1; SMN2TSHRTP53 | |
| SCHEMBL15943384 | 0.77 | LMNA (0.46) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003242-B | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2015-04-22 | — | — | CN | claimed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | claimed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | claimed |
| EP-2595957-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-05-29 | — | — | EP | claimed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | claimed |
| CN-103003242-A | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | claimed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | claimed |
| CN-103003242-B | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2015-04-22 | — | — | CN | disclosed |
| CN-103003242-B | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2015-04-22 | — | — | CN | disclosed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | disclosed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| CN-103003242-A | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | disclosed |
| CN-103003242-A | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | VCAM1, ICAM1, CCL5 | ALDH1A1 634/4885LMNA 1729/4885MAPT 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.