Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552412 | 0.83 | MAPT (0.40) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL28592964 | 0.77 | MAPT (0.35) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL3193087 | 0.76 | ALOX15 (0.42) | MAPTGAARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL858689 | 0.76 | MAPT (0.45) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL6098708 | 0.75 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL27291094 | 0.74 | MAPT (0.44) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL4775993 | 0.72 | MAPT (0.41) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| SCHEMBL27819720 | 0.71 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2P2RX4 | |
| Hydrochloric Acid SCHEMBL28604267 | 0.71 | GAA (0.44) | MAPTGAATSHR | |
| SCHEMBL8330072 | 0.70 | MAPT (0.47) | MAPTGAARAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999312-A | Anti-transferrin receptor antibodies with tailored affinity | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-107810199-B | Anti-transferrin receptor antibodies with tailored affinity | 豪夫迈·罗氏有限公司 | 2021-11-09 | — | — | CN | disclosed |