SCHEMBL28660261

SCHEMBL28660261

C=C(COCC(=C)c1ccco1)c1ccco1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
KMT2A Q03164 4/20 0.41
PTPN1 P18031 1/20 0.41
ALDH1A1 P00352 6/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
APEX1 P27695 1/20 0.39
HPGD P15428 2/20 0.39
ERCC5 P28715 1/20 0.39
FEN1 P39748 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 1/20 0.38
PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14797763 0.89 NPC1 (0.40) CES2CES1KMT2APTPN1ALDH1A1
SCHEMBL14797981 0.86 KMT2A (0.43) CES2CES1KMT2APTPN1ALDH1A1
SCHEMBL14798032 0.84 CES2 (0.47) CES2CES1KMT2APTPN1ALDH1A1
SCHEMBL14798139 0.83 KMT2A (0.47) KMT2AALDH1A1POLBMEN1HPGD
SCHEMBL14798145 0.81 TSHR (0.43) CES2KMT2AALDH1A1POLBMEN1
SCHEMBL11360228 0.78
SCHEMBL14797845 0.78 ALDH1A1 (0.51) CES2CES1KMT2APTPN1ALDH1A1
SCHEMBL6519341 0.77
SCHEMBL6531416 0.77
Hydrochloric Acid SCHEMBL10367671 0.75 CES2 (0.45) CES2CES1KMT2APTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717209-A Synthesis method of alkyl silicon compound 南通大学 2021-11-30 CN disclosed