Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 7/20 | 0.56 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | BLVRB | P30043 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672541 | 0.84 | CDC7 (0.65) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL28653714 | 0.84 | XDH (0.43) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL28677825 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL28660406 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL28672534 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL28658387 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL28660331 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL27875453 | 0.78 | CDC7 (0.63) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL19523322 | 0.77 | XDH (0.63) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 | |
| SCHEMBL438271 | 0.77 | XDH (0.68) | SMN1; SMN2XDHTARBP2ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024534-B | 2-pyridylthiazole derivatives and use thereof | 武汉光谷亚太医药研究院有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-113024534-A | 2-pyridylthiazole derivatives and use thereof | 武汉光谷亚太医药研究院有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-113024534-B | 2-pyridylthiazole derivatives and use thereof | 武汉光谷亚太医药研究院有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-113024534-A | 2-pyridylthiazole derivatives and use thereof | 武汉光谷亚太医药研究院有限公司 | 2021-06-25 | — | — | CN | disclosed |