Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929167 | 0.74 | EGFR (0.40) | ALKEGFR | |
| SCHEMBL28655649 | 0.71 | PDE10A (0.44) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28929166 | 0.69 | — | — | |
| SCHEMBL10086618 | 0.66 | HIF1A (0.60) | HTR1ASLC6A2APP | |
| SCHEMBL28660399 | 0.65 | ALDH1A1 (0.39) | ALK | |
| SCHEMBL7495157 | 0.64 | HTR1A (0.74) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19703133 | 0.64 | HTR2C (0.57) | HTR1ASLC6A2SLC6A4SLC6A3CCNT1 | |
| SCHEMBL28654896 | 0.64 | BRD4 (0.45) | CDK9EGFRAPP | |
| SCHEMBL30735726 | 0.64 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19297109 | 0.64 | HTR1A (0.51) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | claimed |
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | disclosed |