Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663835 | 0.86 | KDM4E (0.42) | EGFRFGFR3FGFR2TP53KDM4E | |
| SCHEMBL28929164 | 0.81 | CHEK1 (0.43) | JAK2TYK2INSRALKKCNH2 | |
| SCHEMBL28660403 | 0.74 | HTR1A (0.42) | EGFRALK | |
| SCHEMBL28672740 | 0.71 | ALDH1A1 (0.48) | HTTMAPTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL28660399 | 0.71 | ALDH1A1 (0.39) | LMNAMAPTSMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL28654896 | 0.70 | BRD4 (0.45) | EGFRFGFR3TNIK | |
| SCHEMBL28663832 | 0.67 | INSR (0.46) | JAK2INSRALKKCNH2TNIK | |
| SCHEMBL22970837 | 0.67 | POLB (0.48) | MAPTSMN1; SMN2ALOX15MAPK1RAB9A | |
| SCHEMBL28445775 | 0.67 | AURKA (0.47) | EGFRKDM4ETYK2POLBNPSR1 | |
| SCHEMBL28663676 | 0.67 | ALDH1A1 (0.45) | SMN1; SMN2ALOX15POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | claimed |
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | disclosed |