Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28663832 | 0.89 | INSR (0.46) | BRD4TNIKIKBKETBK1 | |
| SCHEMBL28654896 | 0.86 | BRD4 (0.45) | BRD4TNIKHRH4IKBKETBK1 | |
| SCHEMBL28660399 | 0.77 | ALDH1A1 (0.39) | BRD4HRH4 | |
| SCHEMBL28929164 | 0.75 | CHEK1 (0.43) | TNIKIKBKETBK1 | |
| SCHEMBL28653790 | 0.72 | HTR2C (0.39) | BRD4EGFR | |
| SCHEMBL30340921 | 0.71 | IGF1R (0.54) | TNIKFGFR3EGFRERBB3 | |
| SCHEMBL28677765 | 0.71 | HRH4 (0.51) | HRH4IKBKETBK1EGFRKDM1A | |
| SCHEMBL28663834 | 0.71 | CCNT1 (0.43) | — | |
| SCHEMBL28053990 | 0.70 | ALK (0.59) | BRD4FGFR3EGFR | |
| SCHEMBL28663835 | 0.69 | KDM4E (0.42) | TNIKFGFR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | claimed |
| CN-113717158-A | 2- (N- (pyridine-2-yl) amino) quinoline derivative and application thereof | 河南省人民医院 | 2021-11-30 | — | — | CN | disclosed |