Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397408 | 0.85 | AKR1C3 (0.51) | MAPTALOX15ALOX5ALDH1A1GAA | |
| SCHEMBL7852387 | 0.84 | MAPT (0.71) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL8025393 | 0.84 | MAPT (0.71) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL902692 | 0.83 | AKR1C3 (0.64) | MAPTALOX15KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL384593 | 0.83 | FABP4 (0.65) | ALDH1A1RAB9ANPC1SIRT2P2RX1 | |
| SCHEMBL17617073 | 0.83 | MAPT (0.76) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL31914 | 0.82 | MAPT (1.00) | MAPTALOX15KDM4EPOLBATM | |
| SCHEMBL28665583 | 0.82 | MAPT (0.69) | MAPTALOX15ALOX5KDM4EPOLB | |
| SCHEMBL28672723 | 0.82 | MAPT (0.69) | MAPTALOX15ALOX5KDM4EPOLB | |
| SCHEMBL22453219 | 0.81 | MAPT (0.72) | MAPTALOX15KDM4EPOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113768936-B | Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection | 南华大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-113768936-A | Application of evodiamine derivative in preparation of medicine for treating superficial fungal infection | 南华大学 | 2021-12-10 | — | — | CN | disclosed |