SCHEMBL31914

SCHEMBL31914

COC(=O)c1ccccc1Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
ALOX15 P16050 1/20 1.00
KDM4E B2RXH2 5/20 0.65
POLB P06746 1/20 0.65
ATM Q13315 1/20 0.65
FABP4 P15090 1/20 0.62
SIRT2 Q8IXJ6 1/20 0.62
CXCR2 P25025 1/20 0.60
KMT2A Q03164 2/20 0.59
GLA P06280 1/20 0.56
MEN1 O00255 1/20 0.55
HTT P42858 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PTGS2 P35354 1/20 0.54
TSHR P16473 3/20 0.53
LMNA P02545 1/20 0.53
HSD17B10 Q99714 4/20 0.53
GAA P10253 3/20 0.53
MAPK1 P28482 1/20 0.53
ALDH1A1 P00352 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13224505 0.94 MAPT (0.89) MAPTALOX15KDM4EPOLBATM
SCHEMBL28649151 0.90 MAPT (0.81) MAPTALOX15KDM4EPOLBATM
SCHEMBL12109319 0.89 MAPT (0.81) MAPTALOX15KDM4EPOLBATM
SCHEMBL22445145 0.89 MAPT (0.79) MAPTALOX15KDM4EPOLBATM
SCHEMBL31168050 0.89 MAPT (0.79) MAPTALOX15KDM4EPOLBATM
SCHEMBL19065779 0.88 MAPT (0.79) MAPTALOX15KDM4EPOLBATM
SCHEMBL28658698 0.88 MAPT (0.78) MAPTALOX15KDM4EPOLBATM
SCHEMBL4544793 0.87 MAPT (0.77) MAPTALOX15KDM4EPOLBATM
SCHEMBL22853361 0.86 MAPT (0.76) MAPTALOX15KDM4EPOLBATM
SCHEMBL22452889 0.86 MAPT (0.76) MAPTALOX15KDM4EPOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105647515-B A kind of dendroid thermal activation delayed fluorescence material and its synthetic method 华南理工大学 2017-10-20 CN claimed
CN-104611134-B Lychee flavor 浙江绿晶香精有限公司 2017-06-09 CN claimed
CN-105647515-A Dendritic thermal activation delay fluorescence material and synthesizing method thereof 华南理工大学 2016-06-08 CN claimed
CN-103974621-A Pest control formulations and methods of making and using the same 0903608 B C LTD 2014-08-06 CN claimed
CN-101562978-B herbicidal composition SYNGENTA PARTICIPATIONS AG 2014-04-02 CN claimed
CN-103524362-A Malachite green artificial antigen and antibody, and preparation method and application thereof UNIV SHENZHEN 2014-01-22 CN claimed
CN-103384528-A Biodegradable Drug Delivery Compositions DURECT CORP 2013-11-06 CN claimed
CN-101296710-B Aerosol compositions and methods RECKITT BENCKISER UK LTD (GB) 2012-12-12 CN claimed
CN-102043031-B Propolis supercritical CO2 extract GC-MS fingerprint and construction method thereof UNIV JIANGSU 2012-08-29 CN claimed
CN-102060767-B Method for producing caprolactam by methylbenzene DALIAN CHEMICAL PHYSICS INST 2012-08-22 CN claimed
CN-1688681-A Protection of fragrance in a wax candle using an antioxidant BELME CO (US) 2005-10-26 CN claimed
CN-1606408-A Ambient stable beverage UNILEVER NV (NL) 2005-04-13 CN claimed
CN-1174741-C Surface-modified microparticle compositions of biologically active substances RTPҩƷ��˾ 2004-11-10 CN claimed
CN-1438858-A Biodegradable carrier and delivery system for biologically active substances SHUKLA A J (US) 2003-08-27 CN claimed
CN-1103216-C Pharmaceutical emulsions containing bioactive steroids PHARMACIA AB (SE) 2003-03-19 CN claimed
CN-1384734-A Surface-modified microparticle compositions of biologically active substances RTP PHARMA INC (US) 2002-12-11 CN claimed
CN-1332016-A Biodegradable carrier and biodegradable delivery system A J SCHUCKRA (US) 2002-01-23 CN claimed
CN-1058840-C An arthropod control composition for plant protection ISRAEL STATE (IL) 2000-11-29 CN claimed
CN-1266349-A Composition for preventing and treating dust mite and allergen thereof RECKITT & COLMAN INC (US) 2000-09-13 CN claimed
CN-1093221-A The arthropod control composition that is used for plant protection ISRAEL STATE (IL) 1994-10-12 CN claimed