SCHEMBL384593

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7572551	0.89	CXCR2 (0.63)	FABP4TAS2R14PTGS1AKR1C3AKR1C2
	SCHEMBL338231	0.86	P2RX1 (0.62)	SIRT2SIRT1ALDH1A1P2RX1HTT
	SCHEMBL28660772	0.83	MAPT (0.69)	PTGS2SIRT2SIRT1ALDH1A1P2RX1
	Fenamic Acid SCHEMBL25828	0.82	FABP4 (0.92)	FABP4TAS2R14PTGS1AKR1C3AKR1C2
	Fenamic Acid SCHEMBL29622832	0.82	FABP4 (0.92)	FABP4TAS2R14PTGS1AKR1C3AKR1C2
	SCHEMBL15673372	0.82	SIRT2 (0.77)	FABP4TAS2R14PTGS1AKR1C3AKR1C2
	SCHEMBL2294168	0.82	AKR1C3 (0.67)	FABP4TAS2R14PTGS1AKR1C3AKR1C2
	SCHEMBL9719838	0.82	FABP4 (0.67)	FABP4TAS2R14PTGS1AKR1C3AKR1C2
	SCHEMBL383535	0.82	GRIK1 (0.74)	AKR1C3AKR1C2MPOGRIK1GRIK2
	SCHEMBL15397409	0.82	AKR1C3 (0.60)	AKR1C3AKR1C2MPOGRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.