Hydroxyamine

Hydroxyamine

SCHEMBL28660962

C=Cc1ccc(C(F)(F)F)cc1Cl.NO

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 3/20 0.49
ALDH1A1 P00352 4/20 0.43
MAPT P10636 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
BACE1 P56817 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EPHX2 P34913 1/20 0.37
SCN4A P35499 1/20 0.37
AHR P35869 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9996686 0.94 PDE2A (0.49) PDE2AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL16951055 0.79 PDE2A (0.44) PDE2AALDH1A1MAPTHTTSMN1; SMN2
SCHEMBL29254639 0.77 PDE2A (0.46) PDE2AALDH1A1MAPTCYP1A2CYP2D6
Methyl Benzoate SCHEMBL9473070 0.77 MRGPRX4 (0.52) ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
SCHEMBL952008 0.76 TDP1 (0.55) PDE2AALDH1A1MAPTBACE1KDM4E
SCHEMBL9996684 0.76 PDE2A (0.44) PDE2AALDH1A1MAPTCYP1A2CYP2D6
SCHEMBL19145485 0.76 ALDH1A1 (0.46) ALDH1A1MAPTBACE1KDM4EEPHX2
SCHEMBL3146888 0.76 ALDH1A1 (0.43) PDE2AALDH1A1MAPTCYP2C19KDM4E
SCHEMBL4373756 0.75 PDE2A (0.45) PDE2AALDH1A1MAPTCYP1A2CYP2C19
SCHEMBL13707569 0.75 PDE2A (0.45) PDE2AALDH1A1MAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113660983-A Carbamate derivatives and uses thereof 诺瑟拉有限公司 2021-11-16 CN disclosed