Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.50 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613833 | 0.99 | SQOR (0.52) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL8913283 | 0.99 | SQOR (0.52) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL28687653 | 0.93 | LMNA (0.49) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL28457833 | 0.90 | LMNA (0.53) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL28861289 | 0.83 | TK1 (0.47) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11397642 | 0.80 | LMNA (0.62) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11398673 | 0.79 | LMNA (0.61) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11397990 | 0.79 | LMNA (0.61) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11400022 | 0.79 | LMNA (0.61) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11393256 | 0.79 | LMNA (0.61) | SQORLMNASMN1; SMN2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761915-B | 5-fluorouracil ester-forming prodrugs targeting the MCT1 transporter | 沈阳药科大学 | 2021-12-21 | — | — | CN | disclosed |