Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13513241 | 0.94 | LMNA (0.63) | MAPTL3MBTL1LMNASRD5A2MAOB | |
| SCHEMBL7129800 | 0.89 | MAPT (0.80) | MAPTL3MBTL1SRD5A2SMN1; SMN2STS | |
| Methyl Alcohol SCHEMBL11602292 | 0.85 | MAPT (0.68) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL24800 | 0.85 | MAPT (0.73) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL1515693 | 0.84 | L3MBTL1 (0.68) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL8033816 | 0.83 | SRD5A2 (0.89) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL5260372 | 0.83 | SRD5A2 (0.89) | MAPTL3MBTL1SRD5A2SMN1; SMN2STS | |
| Water SCHEMBL9243001 | 0.83 | MAPT (0.70) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 | |
| Water SCHEMBL20527670 | 0.83 | MAPT (0.70) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 | |
| SCHEMBL4282905 | 0.83 | MAPT (0.70) | MAPTL3MBTL1LMNASRD5A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438384-B | Polysubstituted 2, 4-diaryl thiazole and derivative and synthetic method thereof | 湘潭大学 | 2021-10-22 | — | — | CN | claimed |
| CN-109438384-B | Polysubstituted 2, 4-diaryl thiazole and derivative and synthetic method thereof | 湘潭大学 | 2021-10-22 | — | — | CN | disclosed |