Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD10 | O75832 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14979975 | 0.77 | CYP24A1 (0.44) | PSMD10CYP24A1CA12CA1CA9 | |
| SCHEMBL26813651 | 0.74 | CPB2 (0.45) | ADAMTS5MEN1KMT2AALDH1A1 | |
| SCHEMBL26813648 | 0.74 | CPB2 (0.42) | ADAMTS5MEN1KMT2A | |
| SCHEMBL28579686 | 0.73 | MEN1 (0.41) | ADAMTS5MEN1KMT2A | |
| SCHEMBL29768658 | 0.72 | PSMD10 (0.59) | PSMD10MEN1KMT2ASTAT3ALDH1A1 | |
| SCHEMBL24842800 | 0.72 | MEN1 (0.40) | ADAMTS5MEN1KMT2A | |
| SCHEMBL24842023 | 0.72 | MEN1 (0.40) | ADAMTS5MEN1KMT2A | |
| SCHEMBL28583235 | 0.72 | MEN1 (0.40) | ADAMTS5MEN1KMT2A | |
| SCHEMBL20139133 | 0.71 | MEN1 (0.42) | ADAMTS5MEN1KMT2AALDH1A1 | |
| SCHEMBL26215218 | 0.71 | GAA (0.48) | KMT2ACA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784969-A | PLK1 Selective degradation inducing Compounds | 厄普特拉公司 | 2021-12-10 | — | — | CN | disclosed |