Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | MMP13 | P45452 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10106374 | 0.87 | ALOX5 (0.56) | PPARGHPGDNPC1RAB9A | |
| SCHEMBL28656783 | 0.84 | EPHX2 (0.60) | MAPK14PPARGHPGDEPHX2LMNA | |
| SCHEMBL27472366 | 0.83 | ALOX5 (0.61) | PPARGHPGDNPC1RAB9A | |
| SCHEMBL28651771 | 0.82 | EPHX2 (0.64) | PPARGHPGDEPHX2LMNA | |
| SCHEMBL28926992 | 0.80 | EPHX2 (0.62) | PPARGEPHX2 | |
| SCHEMBL22987223 | 0.80 | HPGD (0.74) | MAPK14PPARGPPARAHPGDEPHX2 | |
| SCHEMBL31061058 | 0.80 | MAPK14 (1.00) | MAPK14PPARGPPARAHPGDEPHX2 | |
| SCHEMBL6257688 | 0.80 | MAPK14 (0.84) | MAPK14PPARGPPARAHPGDEPHX2 | |
| SCHEMBL1747191 | 0.79 | HDAC1 (0.69) | HPGDEPHX2SMN1; SMN2LMNANPC1 | |
| SCHEMBL2773677 | 0.78 | FFAR1 (0.66) | HPGDEPHX2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |