Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651771 | 0.89 | EPHX2 (0.64) | EPHX2CYP4F2CYP4A11CYP4Z1ALDH1A1 | |
| SCHEMBL28643158 | 0.83 | EPHX2 (0.66) | EPHX2CYP4F2CYP4A11PPARG | |
| SCHEMBL28663154 | 0.80 | MAPK14 (0.65) | EPHX2PPARG | |
| SCHEMBL28656783 | 0.80 | EPHX2 (0.60) | EPHX2CYP4Z1PPARGGAAMAPK1 | |
| SCHEMBL11911407 | 0.78 | CYP4F2 (0.69) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL22987232 | 0.78 | EPHX2 (0.67) | EPHX2KMT2AALDH1A1PPARG | |
| SCHEMBL9157019 | 0.76 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP4Z1ALDH1A1GAA | |
| SCHEMBL6328999 | 0.74 | ALOX5 (0.69) | CYP4F2CYP4A11CYP4Z1ALDH1A1TDP1 | |
| SCHEMBL9671800 | 0.74 | CYP4Z1 (0.65) | CYP4F2CYP4A11CYP4Z1ALDH1A1PPARG | |
| SCHEMBL28665658 | 0.73 | KMT2A (0.65) | EPHX2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |