Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330958 | 0.86 | CYP4Z1 (0.59) | LMNACYP4Z1CYP3A4HPGDGAA | |
| SCHEMBL28663154 | 0.84 | MAPK14 (0.65) | EPHX2PPARGLMNANPC1RAB9A | |
| SCHEMBL5871481 | 0.82 | CYP4F2 (0.58) | LMNACYP4Z1HPGDGAAMAPK1 | |
| SCHEMBL28651771 | 0.81 | EPHX2 (0.64) | EPHX2PPARGLMNACYP4Z1HPGD | |
| SCHEMBL28643158 | 0.80 | EPHX2 (0.66) | EPHX2PPARGHPGD | |
| SCHEMBL28926992 | 0.80 | EPHX2 (0.62) | EPHX2PPARGCYP4Z1GAAMAPK1 | |
| SCHEMBL14393711 | 0.79 | LMNA (0.67) | EPHX2PPARGLMNAL3MBTL1NPC1 | |
| SCHEMBL9671800 | 0.77 | CYP4Z1 (0.65) | PPARGCYP4Z1CYP3A4GAAMAPK1 | |
| SCHEMBL6077802 | 0.77 | L3MBTL1 (0.77) | EPHX2PPARGLMNAL3MBTL1POLB | |
| SCHEMBL11982117 | 0.76 | MAPT (0.60) | EPHX2L3MBTL1CYP4Z1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |